Wednesday, September 9, 2020

Rain dance

© Associated Press
Click to enlarge

California’s winter rains usually end in March or April and begin again in October or November – although these days that varies. This year, that schedule is catastrophic. 
With more than 14,000 firefighters battling hundreds of fires around California and more than 2 million acres already burned, let’s dance, pray, beg for rain.

News blues…

After a typically dry summer, California is parched heading into fall and what normally is the most dangerous time for wildfires. Two of the three largest fires in state history are burning in the San Francisco Bay Area [population more than 7 million].
A three-day heat wave brought triple-digit temperatures to much of the state during Labor Day weekend. But right behind it was a weather system with dry winds that could fan fires. The state’s largest utility, Pacific Gas & Electric, was preparing to cut power to 158,000 customers in 21 counties in the northern half of the state to reduce the possibility its lines and other equipment could spark new fires.
Randy Moore, regional forester for the Forest Service’s Pacific Southwest Region that covers California, announced campgrounds at all national forests in the state also were closed. “The wildfire situation throughout California is dangerous and must be taken seriously. Existing fires are displaying extreme fire behavior, new fire starts are likely, weather conditions are worsening, and we simply do not have enough resources to fully fight and contain every fire.”
Record-breaking temperatures were driving the highest power use of the year, and transmission losses because of wildfires have cut into supplies. Throughout the holiday weekend, the California Independent System Operator that manages the state’s power grid warned of outages if residents didn’t reduce their electricity usage. 
*** 
With scores of pharma companies working on a vaccine against Covid-19,  spokesperson for AstraZeneca, the company working with a team from Oxford University, explained the trial has been stopped to review the “potentially unexplained illness” in one of the participants.
The spokesman stressed that the adverse reaction was only recorded in a single participant and said pausing trials was common during vaccine development.
“As part of the ongoing randomised, controlled global trials of the Oxford coronavirus vaccine, our standard review process was triggered and we voluntarily paused vaccination to allow review of safety data by an independent committee.”
“This is a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials. In large trials illnesses will happen by chance but must be independently reviewed to check this carefully. “We are working to expedite the review of the single event to minimise any potential impact on the trial timeline. We are committed to the safety of our participants and the highest standards of conduct in our trials.”
The vaccine had been expected to be publicly available as early as January.
On the other hand,
Pfizer and BioNTech are confident they can have a vaccine against the novel coronavirus ready for regulatory approval by the middle of October or early November, [said] BioNTech CEO and co-founder Ugur Sahin. "It has an excellent profile and I consider this vaccine ... near perfect, and which has a near perfect profile."
US drug giant Pfizer and German firm BioNTech say they plan to provide 100 million doses of their vaccine candidate, BNT162, by the end of the year, and up to 1.3 billion doses in 2021. How are vaccines tested? 
In the pre-clinical stage of testing, researchers give the vaccine to animals to see if it triggers an immune response. 
  • In phase 1 of clinical testing, the vaccine is given to a small group of people to determine whether it is safe and to learn more about the immune response it provokes.
  • In phase 2, the vaccine is given to hundreds of people so scientists can learn more about its safety and correct dosage.
  • In phase 3, the vaccine is given to thousands of people to confirm its safety – including rare side effects – and effectiveness. These trials involve a control group which is given a placebo.
Take aways?
Excessive heat. Excessive fire danger. Excessive death and illness. Who knows what will happen next?
One thing for sure: we’re living in unprecedented times. But we’re doing it. We will survive. (Let’s hear it, Gloria Gaynor.  (3:12 mins)
***
The Lincoln Project: Fallen Heroes  (2:00 mins)
Radicalize  (0:55 mins)
Trump is not like you  (2:15 mins)

Meanwhile, back at the ranch…

Hard day in the house, sad day, too. Three dogs down. Yes, three elderly, incontinent dogs but my mom loves ‘em. Now they’re elderly, incontinent doggie angels in doggie heaven. Happy sad? 

The move is moving along. This time next week, my mom will start another phase of her life. She’ll adjust and, I believe, even enjoy the company once she settles in.
And I’m saying a   L O N G  goodbye to the plants I’ve nurtured in the garden lo, these many months.


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